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Week 4 NFL Predictions

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THURSDAY, SEPT. 26

8:25 PM ET

49ERS (1-2) AT RAMS (1-2)

This is the 128th meeting of the two teams. The series is as close as it can get … each team has won 62 games and there have been three ties. Each team has won two of the last five games and there was one tie. The Rams are 8-5 versus the 49ers in St. Louis. The last three games were decided by a total of 10 points. — Jerry Tapp

This is a must-win game for Jim Harbaugh’s dinged-up group. If Colin Kaepernick can’t get up for this one, cancel those Super Bowl reservations. — Mike Greger

49ers Rams
Stan Chrapowicki, AFC West Editor x
Zach Doleiden, NFC South Editor x
Mike Greger, NFC West Editor x
Josh Grossman, NFC North Editor x
Allen Kim, NFC East Editor x
Shaun Koh, AFC East Editor x
Brett Spielberg, AFC South Editor x
Danny Webster, NFC North Editor x