Premier League preview: Tottenham v Wigan
Andre Villas-Boas' side are fourth on the table with 17 points, four points behind Manchester City and Manchester United and five points behind leaders Chelsea.
However, Tottenham have made a shaky start to the season at White Hart Lane, managing just two wins and two draws from five matches at home.
Adding to their woes, Tottenham were stunned in the Capital One Cup on Wednesday, going down to Premier League rivals Norwich City 2-1 at Carrow Road.
"We set out to try and win this game and to let it slip in the end is difficult for everyone," Villas-Boas told Tottenham's website.
"But we move on and focus on Wigan now."
Wigan suffered a bigger blow in the Capital One Cup after being eliminated by League Two outfit Bradford City on Tuesday.
Roberto Martinez's men dominated possession at the DW Stadium but were unable to find a way past goalkeeper Matt Duke before bowing out in a penalty shootout.
"The whole team are very disappointed, we had players in the team who were desperate for minutes on the pitch and to make an impact on the team," Martinez told Wigan's website.
"But we'll look back on exiting the cup having not lost the game in normal time and after being the better side throughout the match, but just lacking the final touch."
Wigan, in 15th on eight points, are aiming for their second straight win in the league, having accounted for West Ham United 2-1 last week.