Serie A preview: Inter, Juve in top-of-the-table showdown
Inter Milan head to Juventus in a battle of Serie A's top two looking for a ninth straight win and to end the leaders' 49-game undefeated streak.
Juventus head Inter by four with 28 points from a possible 30 to start the season but many feel the visitors are best primed to end the staggering sequence as Juve eye AC Milan's 58-game record league streak.
Andrea Stramaccioni's Inter will arrive at Juventus Arena in ominous form on Saturday with the latest triumph - a 3-2 result against Sampdoria - perhaps the most promising sign on their path of development.
"The best thing to emerge from this is that we're improving," Stramaccioni said after the Sampdoria result.
"Tonight I saw our best performance yet in terms of the football we produced.
"When it comes to (Juventus) on Saturday, I'm lucky because I'm relatively calm, perhaps I'm not aware of the significance of it."
Struggling AC Milan will look to climb out of the bottom half of the table with victory over Chievo on Saturday after only one win in their past five clashes.
Injury-plagued striker Alexandre Pato could return for Massimiliano Allegri's side to lessen the load on Italian starlet Stephan El Shaarawy, who leads the league with seven goals.
Pescara boss Giovanni Stroppa may be salvaging the remains of his job if his side falls to another defeat at home to a Parma side who have won three straight matches, in the early game on Saturday.
Third-placed Napoli will look to get back on track after their defeat at Atalanta as they host Torino on Sunday.
Roma are also in action on Sunday at home to Palermo having let in more goals than any other side (19) in the opening 10 games, but still sit seventh after back-to-back losses.
In other clashes on Sunday, Atalanta eye a third win in four games on their travels to injury-ravaged Sampdoria and Bologna try to escape the bottom three at home to Udinese.
Catania welcome Lazio, Fiorentina host Cagliari while bottom side Siena entertain Genoa.