South Carolina must prepare to face No. 5 Missouri without starting quarterback Connor Shaw.
Shaw sprained his knee in the fourth quarter of a loss to Tennessee on Saturday. An MRI did not show any torn ligaments.
Coach Steve Spurrier ruled Shaw out of practice for at least the first two days this week, though the quarterback is walking with a knee brace.
"I'm sort of doubtful he'll be able to do much this week," Spurrier said. "We'll know more about his situation Wednesday or Thursday."
Backup Dylan Thompson isn't a threat to run like Shaw, but has thrown for 1,465 yards, 12 touchdowns and four interceptions in his career.
If the Gamecocks are forced to play without Thompson, it would represent the second consecutive SEC East matchup between backup quarterbacks for Missouri, which may or may not get starter James Franklin (shoulder) back by the end of the year. The Tigers upset Florida on Saturday, playing without starter Jeff Driskel (broken leg).